Searchable abstracts of presentations at key conferences in endocrinology

ea0065p292 | Neuroendocrinology | SFEBES2019

Cabergoline in the treatment of acromegaly: experience from a large pituitary centre

Samperi Irene , Lithgow Kirstie , Chai Shu Teng , Asia Miriam , Ahmed Shahzada , Paluzzi Alessandro , Tsermoulas George , Meade Sara , Sanghera Paul , Toogood Andy , Gittoes Neil , Ayuk John , Karavitaki Niki

Introduction: Cabergoline is one of the medical treatments in acromegaly; it can be used alone or in combination with other available agents.Aim: To review the efficacy of cabergoline in patients with acromegaly treated in our centre.Patients and methods: Patients with acromegaly on cabergoline were identified from our Pituitary Registry. Clinical/laboratory/imaging data were collected and analysed.Results: F...

ea0065p295 | Neuroendocrinology | SFEBES2019

Review of pituitary metastases diagnosed in a large pituitary centre

Lithgow Kirstie , Siqueira Izel , Ayuk John , Toogood Andrew , Gittoes Neil , Senthil Latha , Chew Han Seng , Chavda Swarupsinh , Matthews Tim , Batra Ruchika , Ahmed Shahzada , Khan Neelam , Meade Sara , Sanghera Paul , Paluzzi Alex , Tsermoulas George , Karavitaki Niki

Background: Metastatic disease in the pituitary (PM) is uncommon and the published literature mainly involves case reports and small case series. We aimed to analyze presenting manifestations and outcomes of patients diagnosed with PM in our pituitary centre.Methods: Retrospective review of our Pituitary Registry to identify patients with PM from 2006 to present. Clinical, radiological, and pathological data were collected and analysed.<p class="abst...

ea0077oc1.5 | Reproductive and Neuroendocrinology | SFEBES2021

Is radiotherapy for pituitary adenoma or craniopharyngioma associated with increased risk of second brain tumour? A long-term multi-centre study of 3,679 patients

Hamblin Ross , Vardon Ashley , Akpalu Josephine , Tampourlou Metaxia , Spiliotis Ioannis , Sbardella Emilia , Lynch Julie , Shankaran Vani , Mavilakandy Akash , Gagliardi Irene , Meade Sara , Hobbs Claire , Levy Miles J , Cameron Alison , Grossman Ashley , Rosaria Ambrosio Maria , Chiara Zatelli Maria , Reddy Narendra , Bradley Karin , Murray Robert D , Pal Aparna , Karavitaki Niki

Background: Current conclusions on risk of second brain tumour following radiotherapy for pituitary adenoma or craniopharyngioma are challenged methodologically by small patient sample size, selection biases or lack of appropriate controls.Objective: To ascertain whether radiotherapy for pituitary adenoma or craniopharyngioma is associated with increased second brain tumour risk, through use of appropriate methodology.Design: Multi...

ea0081yi7 | Young Investigator Awards | ECE2022

Radiotherapy for adults with pituitary adenoma or craniopharyngioma is associated with increased risk of second brain tumour : A multi-centre study of 3,613 patients with long-term imaging surveillance

Hamblin Ross , Vardon Ashley , Akpalu Josephine , Tampourlou Metaxia , Spiliotis Ioannis , Sbardella Emilia , Lynch Julie , Shankaran Vani , Mavilakandy Akash , Gagliardi Irene , Meade Sara , Hobbs Claire , Cameron Alison , Levy Miles J , Ayuk John , Grossman Ashley , Ambrosio Maria Rosaria , Zatelli Maria Chiara , Reddy Narendra , Bradley Karin , Murray Robert , Pal Aparna , Karavitaki Niki

Background: The risk of a second brain tumour following radiotherapy for pituitary adenoma or craniopharyngioma in adults is currently unclear. Studies are methodologically limited by small patient sample size, few case events, selection biases or the use of inappropriate controls.Objective: To ascertain whether radiotherapy delivered to adults with pituitary adenoma or craniopharyngioma is associated with an increased second brain tumour risk using appr...